This project, with a total installed cost (TIC) of $60+ million, consisted of a 50,000 sf, three-story, process development facility.
Work involved unit operations for cell culture, large-scale fermentation, purification, and freeze-drying. The primary use of the PDF was to supply conditioned media to develop new technology and manufacturing processes for mammalian cell-derived products to support Immunex’s clinical and commercial manufacturing activities. The facility also included office, lab, and storage space required to support the new facility, as well as modifications to the existing, adjacent Microbial Facility to accommodate a new boiler.
The new facility required a major utility yard expansion which included a 1,680-ton chilled water system, 400 hp high-pressure steam/condensate system, compressed air/drier, and fuel-oil systems. A primary-secondary pumping arrangement, using constant flow primary pumps and variable flow secondary pumps, was utilized. The system components were all automated through a Siemens BAS design.
total installed cost (TIC)
Process Development Facility
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